|Dataset Full Name||Anatomical Tracings of Lesions after Stroke|
Release 1.1 of the Anatomical Tracings of Lesions After Stroke (ATLAS) Dataset is a collection of 304 T1-weighted MRIs (Magnetic Resonance Images) with manually segmented diverse lesions and metadata. ATLAS is designed to provide researchers with a standardized training and a testing dataset for lesion segmentation algorithms on T1-weighted MRIs. It can also be used to compare different lesion segmentation techniques.
The images were collected across 11 research groups worldwide participating in the ENIGMA Stroke Recovery Working Group consortium. Brain lesions were identified and masks manually drawn on each individual brain MRI using MRIcron, an open-source tool for brain imaging visualization. Quality control was performed on each lesion mask by a second tracer, including categorizing lesions. Additional metadata includes qualitative descriptions of the type of stroke, vascular territory, and intensity of white matter disease developed by an expert neuroradiologist.
|Key Terms||Stroke, MRI, Images, Lesion segmentation, Automated lesion segmentation, Masks|
|Sponsoring Agency/Entity||NA||Health Conditions/Disability Measures|
|Disability Measures||NA||Measures/Outcomes of Interest|
|Topics||Neuroimaging, Lesion segmentation, brain structure, T1-weighted images||Sample|
|Sample Population||Convenience sample of stroke patients from 11 locations worldwide.|
|Sample Size/Notes||304 stroke patients|
|Unit of Observation||Individual/Patient|
Asia, Europe, North America
Global including: United States, China, Germany, Norway
|Geographic specificity||NA||Data Collection|
|Data Collection Mode||Clinical data, images|
|Years Collected||Images and data compiled in 2017|
|Data Collection Frequency||Varies with individual patient. Some have multiple MRIs and metadata over time.||Strengths and Limitations|
|Strengths||Large sample of MRI images. In cases with multiple lesions each non-contiguous lesion is identified and masked. Extensive meta-data developed by expert neuroradiologists are available regarding lesion properties and location(s). In some cases longitudinal data is available. Multiple tracers used to ensure data and tracing quality. All image data can be easily accessed using free open source software. Standardized MRI images are available for over three quarters of the cases (n=239).|
|Limitations||No information regarding the lesion(s) impact on individual functioning.||Data Details|
|Data Access Requirements||Data Use Agreement, No Cost|
The Anatomical Tracings of Lesions After Stroke (ATLAS), 2017
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The Rehabilitation Research Cross-dataset Variable Catalog has been developed through the Center for Large Data Research & Data Sharing in Rehabilitation (CLDR). The Center for Large Data Research and Data Sharing in Rehabilitation involves a consortium of investigators from the University of Texas Medical Branch, Cornell University's Yang Tan Institute (YTI), and the University of Michigan. The CLDR is funded by NIH - National Institute of Child Health and Human Development, through the National Center for Medical Rehabilitation Research, the National Institute for Neurological Disorders and Stroke, and the National Institute of Biomedical Imaging and Bioengineering. (P2CHD065702).
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